CD44 Variant Isoform Expression and Breast Cancer Prognosis
โ Scribed by Tokue, Yutaka ;Matsumura, Yasuhiro ;Katsumata, Noriyuki ;Watanabe, Toru ;Tarin, David ;Kakizoe, Tadao
- Book ID
- 108581579
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1998
- Tongue
- English
- Weight
- 341 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0910-5050
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๐ SIMILAR VOLUMES
CD44 is a family of cell surface transmembrane glycoproteins members which differ in the extracellular part by sequences derived by alternative splicing of 10 variant exons (v1-v10). CD44 proteins containing such variant sequences have been implicated in tumor metastasis formation. Here, we have eva
The role of the adhesion molecule CD44 in the natural history of breast cancer is controversial. We investigated the CD44 isoform CD44v5 and CD44v6 concentrations in the cytosol of 90 breast cancer specimens, 9 fibroadenomas and 22 normal breast tissue specimens by means of ELISA. CD44v5 and CD44v6