Stimulation in vitro of murine splenic B cells by lipopolysaccharide, anti-x Sepharose, anti-CD40 or allo-reactive T helper cells all up-regulated CD21 and CD23 surface expression. Neither anti-CD21 nor anti-CD23 antibodies induced B cell growth or differentiation when added in soluble form or coupl
CD40 ligand-positive CD8+ T cell clones allow B cell growth and differentiation
β Scribed by Patrice Hermann; Cees Van-Kooten; Claude Gaillard; Jacques Banchereau; Dominique Blanchard
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 608 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0014-2980
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B cell differentiation depends on cellular interactions with T lymphocytes and monocytes via adhesion molecules (AM). In order to characterize AM which are required for B cell differentiation immunoglobulin production using unseparated peripheral blood mononuclear cells (PBMC) was studied. Unstimula