CD4 T cells guarantee optimal competitive fitness of CD8 memory T cells
✍ Scribed by Pål Johansen; Panagiota Stamou; Ricardo E. Tascon; Douglas B. Lowrie; Brigitta Stockinger
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 152 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0014-2980
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## Abstract CD4^+^ T cell help during the priming of CD8^+^ T lymphocytes imprints the capacity for optimal secondary expansion upon re‐encounter with antigen. Helped memory CD8^+^ T cells rapidly expand in response to a secondary antigen exposure, even in the absence of T cell help and, are most e
The enumeration of blood CD4+ (single-positive) T cells by flow cytometry is subject to errors such as counting CD4+ monocytes or CD4+CD8+ (double-positive) T cells as CD4+ T cells. Relatively accurate count can be obtained when CD4+ T cells are defined as CD3+CD4+CD8- mononuclear cells (MNCs), usin