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CD4+ T cells and IL-4-mediated support of Th1 immune responses

✍ Scribed by Mark P Rubinstein; David J Cole


Book ID
117787218
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
15 KB
Volume
23
Category
Article
ISSN
1471-4906

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The role of TGF-g 1 in the regulation of T cell responses has been perplexing, possibly because it is dependent on the type of T cell being regulated and its cytokine microenvironment. In the present study, we demonstrate that TGF-g 1 has a profound inhibitory effect on naive CD4 + T cell undergoing