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CD4+ T-Cell and Monocyte Interdependence During Discordant Xenoimmune Responses

✍ Scribed by Y. Fang; Z. Liu; L. Zhu; P. Wang; Y. Wang; H. Xu

Book ID
116934612
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
270 KB
Volume
40
Category
Article
ISSN
0041-1345

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## Abstract 4‐1BBL^–/–^ mice have a defect in recall CD8^+^ T cell responses to viruses, whereas CD4^+^ T cell responses to virus are unimpaired in these mice. In contrast, both CD4^+^ and CD8^+^ T cells respond to 4‐1BB ligand (4‐1BBL) __in vitro__. To clarify the role of 4‐1BB/4‐1BBL in CD4^+^ ve