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CD28/B7 Regulation of Th1 and Th2 Subsets in the Development of Autoimmune Diabetes

✍ Scribed by Deborah J Lenschow; Kevan C Herold; Lesley Rhee; Bina Patel; Ann Koons; Hui-Yu Qin; Elaine Fuchs; Bhagarith Singh; Craig B Thompson; Jeffrey A Bluestone


Book ID
117722705
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
379 KB
Volume
5
Category
Article
ISSN
1074-7613

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Leishmania major infect only macrophages in the host, where they reside in endolysosomal compartments into which MHC class II molecules co-localize. Experimental infection in mice has provided a useful model for the differentiation of T h l CD4+ effector lymphocytes that are required for the generat