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CD-NP, A NOVEL PEPTIDE DESIGNED TO ACTIVATE BOTH GUANYLYL CYCLASE B AND A, ACTIVATES THE SECOND MESSENGER CGMP, SUPPRESSES ALDOSTERONE AND PRESERVES GFR WITHOUT REDUCING BLOOD PRESSURE IN A PROOF-OF-CONCEPT STUDY IN PATIENTS WITH CHRONIC HEART FAILURE

โœ Scribed by Elizabeth Costello; John A. Schirger; Guido Boerrigter; Horng H. Chen; Ruth Kempf; Candace Y. Lee; John C. Burnett Jr

Book ID
118581135
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
240 KB
Volume
57
Category
Article
ISSN
1558-3597

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Cenderitide (CD-NP), a novel peptide des
Cenderitide (CD-NP), a novel peptide designed to activate both guanylyl cyclase B and A, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure in a proof-of-concept study in patients with chronic heart failure
โœ Lisa C Costello-Boerrigter; John A Schirger; Wayne L Miller; Guido Boerrigter; H ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› BioMed Central ๐ŸŒ English โš– 135 KB

Costello-Boerrigter et al.: Cenderitide (CD-NP), a novel peptide designed to activate both guanylyl cyclase B and A, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure in a proof-of-concept study in patients with chronic heart failure.