Interleukin 1 and tumor necrosis factor-a additively increase the levels of granulocyte-macrophage and granulocyte colony-stimulating factor (CSF) mRNA in human fibroblasts\* Recombinant interleukin (IL) 1 p and tumor necrosis factorkachectin (TNF-a) induce, usually within 2 h, a dose-dependent incr
CD and fluorescence studies of the human granulocyte-macrophage colony-stimulating factor and related peptide conformations in aqueous solution
✍ Scribed by L. Casté; M. Zandomeneghi; J. L. Houben; P. Rovero; S. Pegoraro; P. R. Revoltella; J. C. Brochon
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1995
- Tongue
- English
- Weight
- 596 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0006-3525
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is a fellow of Ministerio de Educaci6n y Ciencia. J. Bartolome and J.A. Quiroga are recipients of research grants from Fundacion para el Estudio de las Hepatitis Vudes.
The conformation of the heptacosapeptide hormone, gastrin releasing peptide, has been studied in buffer and in the presence of lipids, using static and dynamic fluorescence and CD. The results obtained show that, in buffer, the hormone exists in a collection of flexible, random coil type conformers,
BACKGROUND. This Phase I study was designed to determine the toxicity and efficacy of a carboplatin and irinotecan (CPT-11) regimen with recombinant human granulocyte colony-stimulating factor (rhG-CSF) support for patients with advanced nonsmall cell lung carcinoma. ## METHODS. Treatment consist