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CCM2 Mediates Death Signaling by the TrkA Receptor Tyrosine Kinase

โœ Scribed by Liraz Harel; Barbara Costa; Marianna Tcherpakov; Marc Zapatka; Andre Oberthuer; Loen M. Hansford; Milijana Vojvodic; Zehava Levy; Zhe-Yu Chen; Francis S. Lee; Smadar Avigad; Isaac Yaniv; Leming Shi; Roland Eils; Matthias Fischer; Benedikt Brors; David R. Kaplan; Mike Fainzilber


Book ID
116783406
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
761 KB
Volume
63
Category
Article
ISSN
0896-6273

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Cell proliferation in response to growth factors is mediated by specific high affinity receptors. Ligand-binding by receptors of the protein tyrosine kinase family results in the stimulation of several intracellular signal transduction pathways. Key signalling enzymes are recruited to the plasma mem