On the preparation of optically active s
✍
Stuart L. Schreiber; Jeff Reagan
📂
Article
📅
1986
🏛
Elsevier Science
🌐
French
⚖ 285 KB
Organocopper reagents react with a chiral nonracemic 1,3-dioxan-4-one to afford substitution products with high diastereoselectivity. After treatment of the adducts with potassium t-butoxide, optically active secondary alcohols are obtained. Recently a new chiral, nonracemic acetal for use in the f