𝔖 Bobbio Scriptorium
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Cbl-b in T-cell activation

✍ Scribed by Magdalena Paolino; Josef M. Penninger


Book ID
105995074
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
371 KB
Volume
32
Category
Article
ISSN
1863-2297

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## Abstract T cell (TC) activation requires the coordinated signaling of the T cell receptor (TCR) and coreceptor molecules, allowing TCs to respond to lower degrees of TCR occupancy. Coreceptor molecules set the threshold for TC activation by controlling different regulatory signaling loops. The C