𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cbl negatively regulates JNK activation and cell death

✍ Scribed by Sproul, Andrew A; Xu, Zhiheng; Wilhelm, Michael; Gire, Stephen; Greene, Lloyd A

Book ID
109847030
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
711 KB
Volume
19
Category
Article
ISSN
0007-0610

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## Abstract T cell (TC) activation requires the coordinated signaling of the T cell receptor (TCR) and coreceptor molecules, allowing TCs to respond to lower degrees of TCR occupancy. Coreceptor molecules set the threshold for TC activation by controlling different regulatory signaling loops. The C