We report the synthesis and labeling with iodine-123 of N-(piperidin-1-yl)-5-(4-iodophenyl)-l-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (AM251). This compound is an analog of the recently described cannabinoid receptor antagonist, SR1417164 in which a 4-chlorophenyl group is replaced b
CB1 cannabinoid receptor antagonism: A new strategy for the treatment of liver fibrosis
β Scribed by Hermann E. Wasmuth; Christian Trautwein
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 183 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
β¦ Synopsis
Alcohol metabolism-mediated oxidative stress downregulates hepcidin transcription and leads to increased duodenal iron transporter expression.
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