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Cause and Consequence of Cancer/Testis Antigen Activation in Cancer

✍ Scribed by Whitehurst, Angelique W.

Book ID: 121476966
Publisher: Annual Reviews
Year: 2014
Tongue: English
Weight: 639 KB
Volume: 54
Category: Article
ISSN: 0362-1642
DOI: 10.1146/annurev-pharmtox-011112-140326

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## Abstract CT45 is a cancer/testis gene that we previously identified by massively parallel signature sequencing. Encoded by a multigene family on chromosome X, CT45 showed restricted mRNA expression to normal testis and various cancers. In this study, monoclonal antibodies were generated against