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Cancer/testis antigen cancer-associated gene (CAGE) promotes motility of cancer cells through activation of focal adhesion kinase (FAK)

✍ Scribed by Hyeeun Shim; Hansoo Lee; Dooil Jeoung


Book ID
106363704
Publisher
Springer Netherlands
Year
2006
Tongue
English
Weight
289 KB
Volume
28
Category
Article
ISSN
0141-5492

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## Abstract Focal adhesion kinase (FAK) is suggested to be intimately involved in the progression of malignancies. Our previous research has demonstrated that activation of cholecystokinin‐2 receptor (CCK2R) by gastrin stimulates a rapid activation of FAK pathway in human colon cancer cells. The pu