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Causal relation between α-synuclein locus duplication as a cause of familial Parkinson's disease

✍ Scribed by P Ibáñez; A-M Bonnet; B Débarges; E Lohmann; F Tison; P Pollak; Y Agid; A Dürr; A Brice

Book ID
117287061
Publisher
The Lancet
Year
2004
Tongue
English
Weight
194 KB
Volume
364
Category
Article
ISSN
0140-6736

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## Abstract The effect of PAMAM dendrimers (generations G3, G4 and G5) on the fibrillation of __α__‐synuclein was examined by fluorescence and CD spectroscopy, TEM and SANS. PAMAM dendrimers inhibited fibrillation of __α__‐synuclein and this effect increased both with generation number and PAMAM co