Cation−π Interaction in Model α-Helical Peptides
✍ Scribed by Shi, Zhengshuang; Olson, C. Anders; Kallenbach, Neville R.
- Book ID
- 127324682
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 167 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0002-7863
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## Abstract The effects on helical stability of weak polar interactions between aromatic side‐chains and the peptide backbone were examined. α‐Helical model peptides, hexa‐Ala, with sequential Tyr replacement, were investigated computationally to obtain the geometries and energetics of the interact
It has come to our attention that both in the online and published version of the above article an error occurred. On page 1210, the last equation, which expresses the CP-corrected interaction energy in solution, was displayed incorrectly. The corrected version of the equation follows. where E(solu
## Abstract The oxygen of a peptide bond has two lone pairs of electrons. One of these lone pairs is poised to interact with the electron‐deficient carbon of the subsequent peptide bond in the chain. Any partial covalency that results from this n→π\* interaction should induce pyramidalization of th