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Cationic trypsinogen mutations and pancreatitis

✍ Scribed by Howes, Nathan; Greenhalf, William; Stocken, Deborah D.; Neoptolemos, John P.


Book ID
122771643
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
270 KB
Volume
33
Category
Article
ISSN
0889-8553

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Hereditary pancreatitis (OMIM 167800) is thought to be associated with a mutation of the exon 3 of cationic trypsinogen (Nature Genet (1996): 14:141-145). This paper reports sequence data of two independent families suffering from this disease. PCR amplificates from leukocyte or buccal swab DNA show

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