𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations

✍ Scribed by Jian-Min Chen; Tristan Montier; Claude Férec

Book ID
106137417
Publisher
Springer
Year
2001
Tongue
English
Weight
106 KB
Volume
109
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mutations of human cationic trypsinogen
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis
✍ Niels Teich; Jonas Rosendahl; Miklós Tóth; Joachim Mössner; Miklós Sahin-Tóth 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 208 KB

Ten years ago, the groundwork for the discovery of the genetic basis of chronic pancreatitis was laid by linkage analyses of large kindreds with autosomal dominant hereditary chronic pancreatitis. Subsequent candidate gene sequencing of the 7q35 chromosome region revealed a strong association of the

Mutations of the cationic trypsinogen in
Mutations of the cationic trypsinogen in hereditary pancreatitis
✍ Niels Teich; Joachim Mössner; Volker Keim 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 168 KB

Hereditary pancreatitis (OMIM 167800) is thought to be associated with a mutation of the exon 3 of cationic trypsinogen (Nature Genet (1996): 14:141-145). This paper reports sequence data of two independent families suffering from this disease. PCR amplificates from leukocyte or buccal swab DNA show

Molecular pathology of primary and metas
Molecular pathology of primary and metastatic ductal pancreatic lesions : Analyses of mutations and expression of the p53, mdm-2, and p21/WAF-1 genes in sporadic and familial lesions
✍ Bruce A. Ruggeri; Lingyi Huang; David Berger; Hong Chang; Andres J. P. Klein-Sza 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 477 KB 👁 2 views

Histologically confirmed specimens of primary (n Å 136) and metastatic icine, Allegheny University of the Health Sci-(n Å 23) sporadic and familial ductal pancreatic adenocarcinoma lesions were ences,