The goal of this work is the development of a rapid and objective matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) method for the quantitation of peptides and proteins in human plasma suitable for use in the Good Laboratory Practices (GLP) environment, where
Cationic Derivatization of Oligosaccharides with Girard's T Reagent for Improved Performance in Matrix-assisted Laser Desorption/Ionization and Electrospray Mass Spectrometry
โ Scribed by T. J. P. Naven; D. J. Harvey
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 470 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0951-4198
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) is shown to give inaccurate results for the analysis of low molecular weight ethoxylate polymers. It is demonstrated that when the degree of ethoxylation is low (n < 9), MALDI-TOFMS produces substantially high
Structural analyses of oligosaccharide-malononitrile derivatives were conducted by matrix-assisted laser desorption/ionization post-source decay (MALDI-PSD) analysis in positive ion mode, and by electrospray ionization collision-induced dissociation (ESI-CID) analysis in negative ion mode. The malon
The performance characteristics of two lasers emitting in the mid infrared, an Er-YAG (2.94 ยตm wavelength, 80-90 ns pulse width), and an Er-YSGG infrared laser (2.79 ยตm wavelength, 80 ns pulse width), in matrix-assisted laser desorption/ionization mass spectrometry (IR-MALDI-MS) of biological macrom
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry of oligosaccharides and gangliosides normally causes loss of sialic acid, particularly when a-cyano-4-hydroxycinnamic acid is used as the matrix. In addition, the potential signal is split because both positive and, to a greater e
A simple mass spectrometric method to sequence a recombinant phosphoenolpyruvate carboxykinase of known structure and a novel variant of unknown structure isolated from Anaerobiospirillum succiniciproducens and Actinobacillus succinogenes 130Z, respectively, was evaluated. The proteolytic digests of