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Catheter-directed Thrombolysis and Thrombectomy for the Budd-Chiari Syndrome in Paroxysmal Nocturnal Hemoglobinuria in Three Patients

✍ Scribed by Kuo, George P.; Brodsky, Robert A.; Kim, Hyun S.


Book ID
122851344
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
244 KB
Volume
17
Category
Article
ISSN
1051-0443

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Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired hemolytic anemia caused by somatic mutations in the phosphatidylinositol glycan-complementation class A gene and the resulting absence of a key complement regulatory protein, CD59. Affected red blood cells in patients with PNH undergo int