Catecholamines and sodium retention in experimental cirrhosis in the rat. Relation to hepatic function
โ Scribed by Wensing, G.; Sabra, R.; Branch, R.A.
- Book ID
- 122664705
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 117 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0168-8278
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Renal sodium handling, assessed by the response to acute saline loading, was investigated in 14 well-compensated, nonascitic alcoholic cirrhotics and six normal controls. Urinary sodium excretion in cirrhotic patients (199 2 14 1 pmoles per min) was significantly lower than in controls (387 f 104 pm
The onset of sodium retention in the phenobarbital and carbon tetrachloride model of cirrhosis in the rat is preceded by a linear decrease in hepatic function as measured by the aminopyrine breath teat. Sodium retention occurs when liver function decreases below a critical threshold. Changes in syst
Recently it was suggested that the onset of sodium retention in experimental cirrhosis in rats is related to a critical threshold of hepatic function, as assessed by the aminopyrine breath test. The aim of this study was to evaluate whether sodium retention occurred after two-thirds hepatectomy in r