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Catechol-O-methyltransferase genotype and susceptibility to Parkinson's disease in Japan

✍ Scribed by A. Yoritaka; N. Hattori; H. Yoshino; Y. Mizuno


Book ID
105147898
Publisher
Springer
Year
1997
Tongue
English
Weight
297 KB
Volume
104
Category
Article
ISSN
1435-1463

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## Abstract Cognitive dysfunction is one of the most incapacitating non‐motor symptoms of Parkinson's disease (PD). Some cognitive deficits are thought to be related to abnormal dopamine homeostasis. The latter is influenced by catechol‐O‐methyltransferase (COMT), an enzyme that degrades dopamine.