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Catechin prevents tamoxifen-induced oxidative stress and biochemical perturbations in mice

✍ Scribed by Suhel Parvez; Heena Tabassum; Hasibur Rehman; Basu Dev Banerjee; Mohammad Athar; Sheikh Raisuddin

Book ID
108287322
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
252 KB
Volume
225
Category
Article
ISSN
0300-483X

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## Abstract Tamoxifen (TAM) is a nonsteroidal triphenylethylene antiestrogenic drug widely used in the treatment and prevention of breast cancer. TAM brings about a collapse of the mitochondrial membrane potential. It acts both as an uncoupling agent and as a powerful inhibitor of mitochondrial ele