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Catalytic sulfur ylide reactions: Use of diazoacetamides for the diastereoselective synthesis of glycidic amides

✍ Scribed by Varinder K. Aggarwal; Paul Blackburn; Robin Fieldhouse; Ray V.H. Jones


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
183 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis


Diazoacetamides react with aldehydes in the presence of catalytic quantities of Cu(aeac)2 (5 tool%) and tetrahydrothiophene (20 tool%) to give glycidic amides in good yields and high diastercoselectivity.


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