✦ LIBER ✦

Catalytic properties of the sperm-specific lactate dehydrogenase (LDH X or C4) from different species

✍ Scribed by Coronel, Carlos E. ;Burgos, Carlos ;Gerez De Burgos, Nelia M. ;Rovai, Leonor E. ;Blanco, Antonio

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 502 KB
Volume: 225
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1402250305

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✦ Synopsis

A comparative study of catalytic properties of the sperm-specific lactate dehydrogenase (EC 1.1.1.27) isozyme X or C4 from a variety of animals (boar, bull, goat, Guinea pig, man, mouse, pigeon, rabbit, and rat) is presented. Optimum concentration and Km values for pyruvate, inhibition by substrate, and activity against analog substrates (a-ketoacids with linear and branched chains from 4 to 6 carbon atoms) for isozyme X of different species showed significant differences. The observed properties are correlated with available evidence on the metabolic role of the enzyme.

LITERATURE CITED

Battellino, L.J., and A. Blanco (1970a) Catalytic properties of the lactate dehydrogenase isozyme X from mouse testis.

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