Catalytic Formation of Oligopeptides from α-Amino Acid Esters with (p-Cymene)ruthenium(II) Complexes

✍ Scribed by Winfried Hoffmüller; Michael Maurus; Kay Severin; Wolfgang Beck

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 384 KB
• Volume: 1998
• Category: Article
• ISSN: 1434-1948
• DOI: 10.1002/(sici)1099-0682(199806)1998:6<729::aid-ejic729>3.0.co;2-m

✦ Synopsis

Consecutive addition of one-equivalent portions of glycine ethyl ester to [(p-cymene)Ru(GGGOMeϪH + )Cl] leads to considerable amounts of (tetra-to nonapeptide)ruthenium complexes in a one-pot reaction, in which the (p-cymene)RuCl fragment acts as a catalyst. The analogous reaction with ala-