Enantiodivergent syntheses of γ-substitu
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Katsufumi Suzuki; Kohei Inomata
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Article
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2003
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Elsevier Science
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French
⚖ 167 KB
Continuous nucleophilic addition with several organometallic reagents to tricyclic lactone (-)-1 proceeded diastereoselectively. Newly generated tertiary and quaternary asymmetric centers were controlled by the order in which the nucleophilic reagents were added. Using this methodology, enantiodiver