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Catalytic asymmetric hydrogenation of dimethyl itaconate with trans-chelating chiral diphosphine ligands TRAP-rhodium complexes

✍ Scribed by Ryoichi Kuwano; Masaya Sawamura; Yoshihiko Ito


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
301 KB
Volume
6
Category
Article
ISSN
0957-4166

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Catalytic asymmetric hydrogenation of 1-
✍ Ryoichi Kuwano; Daisuke Karube; Yoshihiko Ito πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 289 KB

A rhodium complex coordinated with a trans-chelating chiral diphosphine (S,S)-(R,R)-PhTRAP was an effective catalyst for asymmetric hydrogenation of N-acyl-1-aza-2-cycloalkene-2-carboxylates, which gave the corresponding protected cyclic or-amino acids with 73-97% ee.