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Caspase-3 activates endo-exonuclease: Further evidence for a role of the nuclease in apoptosis

✍ Scribed by Xue Wei Meng; M. J. Fraser; J. M. Feller; J. B. Ziegler


Book ID
110275989
Publisher
Springer
Year
2000
Tongue
English
Weight
480 KB
Volume
5
Category
Article
ISSN
1360-8185

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## Abstract In bone, a large proportion of osteoblasts, the cells responsible for deposition of new bone, normally undergo programmed cell death (apoptosis). Because mechanical loading of bone increases the rate of new bone formation, we hypothesized that mechanical stimulation of osteoblasts might