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Caspase-1 is protective during trauma and hemorrhagic shock in mice

✍ Scribed by Christoph L. Menzel; Qian Sun; Hans-Christoph Pape; Timothy R. Billiar; Melanie J. Scott

Book ID
116398986
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
47 KB
Volume
48
Category
Article
ISSN
1043-4666

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TREM-1 promotes survival during septic s
TREM-1 promotes survival during septic shock in mice
✍ SΓ©bastien Gibot; Frederic Massin; Markella Marcou; Valerie Taylor; Ray Stidwill; πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 536 KB

## Abstract Triggering receptor expressed on myeloid (TREM)‐1 is integral to the inflammatory response occurring during septic shock, although its precise function has yet to be determined. Here we show that __in vivo__ silencing of __TREM‐1__ using siRNA duplexes in a fecal peritonitis mouse model