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CASP8AP2 is a novel partner gene of MLL rearrangement with t(6;11)(q15;q23) in acute myeloid leukemia

✍ Scribed by Tae Sung Park; Sang-Guk Lee; Jaewoo Song; Kyung-A Lee; Juwon Kim; Jong Rak Choi; Seung Tae Lee; Rolf Marschalek; Claus Meyer

Book ID: 113513609
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 320 KB
Volume: 195
Category: Article
ISSN: 0165-4608
DOI: 10.1016/j.cancergencyto.2009.06.023

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## Abstract We have identified a novel fusion partner of __MLL__, namely the mastermind like 2 (__MAML____2__ gene), in secondary acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) with inv(11)(q21q23). RT‐PCR and sequencing revealed that exon 7 of __MLL__ was fused to exon 2 of __MAML