✦ LIBER ✦

Case report: Detection of rotavirus RNA in the cerebrospinal fluid of a child with rotavirus gastroenteritis and meningism

✍ Scribed by Prof. Maria Cristina Medici; Laura Anna Abelli; Paola Guerra; Icilio Dodi; Giuseppe Dettori; Carlo Chezzi

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 186 KB
Volume: 83
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.22156

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Although case reports have described detection of rotavirus (RV) in extraintestinal sites such as the liver, kidney, and central nervous system (CNS) of children with RV gastroenteritis, CNS localization in RV infection seems to be rare. RT‐PCR and nucleotide sequencing detected a G1P[8] strain in the stool and cerebrospinal fluid (CSF) samples of a patient with concurrent RV‐associated enteritis and CNS signs. Upon sequence analysis, the viruses detected in the CSF was identical to the virus detected in the stools. In the VP7‐ and VP4‐based phylogenetic dendograms the strain clustered within the G1‐Ic sub‐lineage and the P[8]‐III lineage. This study supports the hypothesis that RV infection was able to spread from the intestinal tract to the CNS, and likely played a role in the onset of neurological disease. J. Med. Virol. 83:1637–1640, 2011. © 2011 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Association of the G4 rotavirus genotype

Association of the G4 rotavirus genotype with gastroenteritis in adults

✍ Susan A. Feeney; Suzanne J. Mitchell; Frederick Mitchell; Dorothy E. Wyatt; Dere 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

Rotavirus is the most common etiological cause of acute viral gastroenteritis in infants and young children worldwide, yet its role in the adult population is less well understood. We have recently identified rotavirus as the causative agent of severe diarrhea in adults, specifically in two gastroen

Hypersegmentation of neutrophils in the

Hypersegmentation of neutrophils in the cerebrospinal fluid: Report of a case with hematologic correlation and review of the literature

✍ R. Daniel Lodge-Rigal; Debra B. Novotny 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB 👁 1 views

## Abstract Hypersegmented neutrophils can occasionally be seen in the cere‐brospinal fluid (CSF) of patients with acute pyogenic meningitis, and rarely as an artifact of cytocentrifugation. We report a case of florid neutrophil hypersegmentation in cytocentrifuged CSF specimens from a patient pres

A study of the prevalence of rotavirus i

A study of the prevalence of rotavirus infection in children with gastroenteritis admitted to an infectious diseases hospital

✍ C. J. Birch; F. A. Lewis; M. L. Kennett; M. Homola; H. Pritchard; Dr. I. D. Gust 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 492 KB 👁 1 views

## Abstract In a 12 month survey of infants and children with gastroenteritis admitted to Fairfield Hospital, Melbourne, rotavirus was found in approximately 42% of patients. This virus was detected more often during the winter months, particularly in children aged between 12 months and 3 years. De

Evaluation of enterovirus serological te

Evaluation of enterovirus serological tests IgM-EIA and complement fixation in patients with meningitis, confirmed by detection of enteroviral RNA by RT-PCR in cerebrospinal fluid

✍ Terletskaia-Ladwig, Elena; Metzger, Christoph; Schalasta, Gunnar; Enders, Gisela 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB 👁 2 views

An enzyme immunoassay (EIA) for detection of anti-enterovirus IgM antibodies was compared with complement fixation test in 43 patients with confirmed enterovirus meningitis by RT-PCR of cerebrospinal fluids (CSF). In 34% of patients with enterovirus meningitis, IgM antibodies could be found, whereas

Detection of JC virus DNA in the cerebro

Detection of JC virus DNA in the cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy

✍ Patricia E. Gibson; Wendy A. Knowles; Julian F. Hand; David W. G. Brown 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 445 KB 👁 1 views

Carcinoma of the pancreas occuring in a

Carcinoma of the pancreas occuring in a child: A case report with description of gray scale ultrasound findings

✍ James B. Masterson; James D. Bowie; Ronald B. Port; Cicely F. Elahi; John D. Bur 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 179 KB 👁 1 views

## Abstract This is a report of the gray scale ultrasound findings of pancreatic carcinoma occurring in a child. Although this tumor is rare, the preoperative diagnosis can be made if the physician is aware of this possibility. ^99m^Tc sulfur colloid radionuclide scan, liver spleen scan, gallium sc