Case control analysis of LRRK2 Gly2385Arg in Alzheimer's disease
β Scribed by E.K. Tan; J. Lee; C.P. Chen; M.C. Wong; Y. Zhao
- Book ID
- 116781182
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 73 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0197-4580
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π SIMILAR VOLUMES
## Abstract A common __LRRK2__ missense variant, Gly2385Arg, has been found to be a genetic risk factor for Parkinson's disease (PD) in ethnic Chinese and Japanese. However, the presence of the variant in other nonβChinese Asian patients has not been fully clarified. We performed genetic analysis o
## Abstract We conducted a caseβcontrol study to determine the prevalence of the __LRRK2__ Gly2385Arg variant in patients with Parkinson's disease in Han population in mainland China. Heterozygous __LRRK2__ Gly2385Arg variant was identified in 14 of 235 patients with Parkinson's disease (5.69%), bu