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LRRK2 Gly2385Arg polymorphism, cigarette smoking, and risk of sporadic Parkinson's disease: A case–control study in Japan

✍ Scribed by Yoshihiro Miyake; Yoshio Tsuboi; Midori Koyanagi; Takahiro Fujimoto; Senji Shirasawa; Chikako Kiyohara; Keiko Tanaka; Wakaba Fukushima; Satoshi Sasaki; Tatsuo Yamada; Tomoko Oeda; Takami Miki; Nobutoshi Kawamura; Nobutaka Sakae; Hidenao Fukuyama; Yoshio Hirota; Masaki Nagai

Book ID: 119303790
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 160 KB
Volume: 297
Category: Article
ISSN: 0022-510X
DOI: 10.1016/j.jns.2010.07.002

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## Abstract Cigarette smoking is associated with reduced monoamine oxidase B (MAO B) activity. Polymorphisms of the __MAO B__ gene may modify the relationship between smoking and Parkinson's Disease (PD). We examined the association of MAO B intron 13 G/A polymorphism and risk of PD, and the modula

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