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Cartilage Matrix Protein: Expression Patterns in Chicken, Mouse, and Human

✍ Scribed by Qian Chen; David M. Johnson; Dominik R. Haudenschild; Paul F. Goetinck

Book ID
119873794
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
330 KB
Volume
785
Category
Article
ISSN
0890-6564

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Over 70 mutations in the cartilage oligomeric matrix protein (COMP), a large extracellular pentameric glycoprotein synthesized by chondrocytes, have been identified as causing two skeletal dysplasias: multiple epiphyseal dysplasia (MED/EDM1), and a dwarfing condition, pseudoachondroplasia (PSACH). T