Carrier Systems for the Local Delivery of Antibiotics in Bone Infections
โ Scribed by Assistant Professor Kyriaki Kanellakopoulou MD, PhD, Evangelos J. Giamarellos-Bourboulis
- Book ID
- 119927396
- Publisher
- Springer International Publishing AG
- Year
- 2000
- Tongue
- English
- Weight
- 204 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0012-6667
No coin nor oath required. For personal study only.
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## Abstract To produce an osteogenic and bacteriocidal biomaterial for the treatment of infected nonunions or bone defects, a synthetic degradable block copolymer of polyโD,Lโlactic acid segments with randomly inserted __p__โdioxanone and polyethylene glycol (PLAโDXโPEG) segments was mixed with rec
## Abstract This study presents a novel biodegradable alginate delivery system for antibiotics and bone cells to treat infected bone defects. About 2 ร 10^7^ New Zealand rabbit mesenchymal stem cells (MSCs) and 5 mL vancomycin solution (50 mg/mL) were added to 5 mL of 2.5% (w/v) sodium alginate sol