Local antibiotic delivery systems for the treatment of osteomyelitis – A review
✍ Scribed by Samit Kumar Nandi; Prasenjit Mukherjee; Subhasis Roy; Biswanath Kundu; Dipak Kumar De; Debabrata Basu
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 227 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0928-4931
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Acute and chronic osteomyelitis can be difficult to treat by conventional means. Current methods of treatment involve the use of systemic antibiotics, the local implantation of non‐degradable drug carriers, and surgical débridement. Each method has specific drawbacks. We report on the u
In this study, a novel antibiotic carrier system for use in the treatment of implant-related and chronic osteomyelitis was developed. Sulbactam-cefoperazone was introduced to rods of polyhydroxybutyrate-co-hydroxyvalerate (22 mol % HV, w/w), a member of a family of microbialorigin polymer that is bi
This study was performed to investigate the potential utility of ofloxacin-impregnated bioabsorbable polymers for osteomyelitis therapy. Pseudomonas aeruginosa osteomyelitis was induced in 48 New Zealand White rabbits. Four weeks after infection, the animals were randomized to one of four treatment
## Abstract A biodegradable, particulate composite bone cement containing gentamicin and vancomycin was used for both treatment and prophylaxis of __Staphylococus aureus__ osteomyelitis in rats. Osteomyelitis was established by inoculating __S. aureus__ into holes that were drilled in the proximal
Composite materials composed of borate bioactive glass and chitosan (designated BGC) were investigated in vitro and in vivo as a new delivery system for teicoplanin in the treatment of chronic osteomyelitis induced by methicillin-resistant Staphylococcus aureus (MRSA). In vitro, the release of teico