<p>For about hundred years the investigation of heart physiology has had one central guiding principle, the "law" of Frank and Starling. This connects the return of blood into the heart and the blood pressure with cardiac conΒ traction force. The "law" does it in a way that enables the cardiovascula
Cardiac Mechanotransduction (Medical Intelligence Unit)
β Scribed by Matti WeckstrΓΆm, Pasi Tavi
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Leaves
- 158
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
This book presents a multidisciplinary approach to cardiac mechanotransduction. The chapters depict the many faces of the topic, from membrane and ion channel level to mechanics, biochemical signaling and regulation via hormone systems. Cardiac Mechanotransduction is of interest to basic life sciences, like physiology, biochemistry and pharmacology, but also to clinicians working with heart-related problems, such as cardiologists and internists.
β¦ Table of Contents
Cover Page......Page 1
Title Page......Page 2
ISBN 0387488677......Page 3
CONTENTS (with page links)......Page 5
CONTRIBUTORS......Page 8
PREFACE......Page 10
Acknowledgments......Page 11
CHAPTER 1 The Mechanosensory Heart: A Multidisciplinary Approach......Page 12
CHAPTER 2 Origin of Mechanotransduction: Stretch-Activated Ion Channels......Page 19
CHAPTER 3 The Role of the Sarcomere and Cytoskeleton in Cardiac Mechanotransduction......Page 39
CHAPTER 4 Mechanoelectric Transduction/Feedback: Physiology and Pathophysiology......Page 59
CHAPTER 5 Mechanotransduction in Girdiac Remodeling and Heart Failure......Page 89
CHAPTER 6 Second Messenger Systems Involved in Heart Mechanotransduction......Page 104
CHAPTER 7 The Role of Adrenoceptors in Mechanotransduction......Page 117
CHAPTER 8 Intracellular Signaling Through Protein Kinases in Cardiac Mechanotransduction......Page 131
CHAPTER 9 Mechanotransduction of the Endocrine Heart: Paracrine and Intracellular Regulation of B-Type Natriuretic Peptide Synthesis......Page 145
Index (with page links)......Page 156
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