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Cardiac electrophysiological effects of levosimendan, a new calcium sensitizer

✍ Scribed by László Virág; Ottó Hála; Anita Marton; András Varró; Julius Gy. Papp

Book ID
113328871
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
573 KB
Volume
27
Category
Article
ISSN
0306-3623

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✍ S. Antila; L. Lehtonen; E.-P. Sandell; J. Eha; M. Heinpalu; I. Loogna; A. Mesike 📂 Article 📅 1996 🏛 Springer 🌐 English ⚖ 746 KB

Objective: Levosimendan in a new inodilator drug that sensitises troponin C in heart muscle cells to calcium, thus improving contractility. In previous studies, a single 2 mg intravenous dose of levosimendan increased cardiac output (CO) in healthy volunteers by about 40% and decreased pulmonary cap