✦ LIBER ✦

Cardiac 123I-MIBG scintigraphy in patients with essential tremor

✍ Scribed by Phil Hyu Lee; Ji Won Kim; Oh Young Bang; In Soo Joo; Seok-Nam Yoon; Kyoon Huh

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 81 KB
Volume: 21
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.20908

No coin nor oath required. For personal study only.

✦ Synopsis

In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using (123)I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of (123)I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 +/- 0.21) than in those with either TDPD (1.28 +/- 0.11) or early PD (1.28 +/- 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.

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