Cardenolides in the latex and leaves of seven Asclepias species and Calotropis procera
β Scribed by James N. Seiber; Carolyn J. Nelson; S.Mark Lee
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 614 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0031-9422
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A protein, similar to osmotin- and thaumatin-like proteins, was purified from Calotropis procera (Ait.) R.Br latex. The isolation procedure required two cation exchange chromatography steps on 50mM Na-acetate buffer (pH 5.0) CM-Sepharose Fast Flow and 25 mM Na-phosphate buffer (pH 6.0) Resource-S, r
The crude dry latex of Calotropis procera possesses a potent antiinflammatory activity. The antiinflammatory activity of petroleum ether, acetone, methanol and aqueous extracts of dry latex of Calotropis procera was tested in the carrageenan induced rat paw oedema model. All the fractions exhibited