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Carcinogenic activity in Sprague-Dawley rats of 2-[3-(2-chloroethyl)-3-nitrosoureido]-D-glucopyranose (chlorozotocin)

✍ Scribed by Habs, M.; Eisenbrand, G.; Schmähl, D.

Book ID
122985916
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
318 KB
Volume
8
Category
Article
ISSN
0304-3835

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Sprague-Dawley rats were given 15, 70 and 140 min exposures to 15 mg/l 3,3-dimethyl-2-butanol, pinacolyl alcohol (PA), or 6-hour exposures to 0.2, 1.0 and 5.0 mg/l PA (1 mg/l = 240 ppm). A 50% mortality rate was obtained at the longest exposure to 15 mg/l. Sex related differences in the blood levels