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Carboxypeptidase Y catalyzed transpeptidation and condensation reactions

โœ Scribed by Klaus Breddam; Jack T. Johansen; Martin Ottesen

Publisher
Springer-Verlag
Year
1984
Weight
389 KB
Volume
49
Category
Article
ISSN
0105-1938

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๐Ÿ“œ SIMILAR VOLUMES

C-Terminal Labeling of Immunoglobulin G
C-Terminal Labeling of Immunoglobulin G with a Cysteine Derivative by Carboxypeptidase Y Catalyzed Transpeptidation
โœ Shiming Lin; Christopher R. Lowe ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 200 KB

We describe a new method for the site-specific incorporation of an extrinsic cysteine to the C-termini of immunoglobulin G (IgG) using carboxypeptidase Y (CPase Y) catalyzed transpeptidation. The transpeptidase activity of CPase Y was employed to attach cysteine esters to the C-termini of the IgG mo