β Scribed by Chia C.H., Talele S.G., Abraham A.R., Haghi A.K. (ed.)
No coin nor oath required. For personal study only.
Recent advancements and research in nanotechnology, biotechnology, materials engineering the applications of nanomaterial are evolving. Carbon nanotubes (CNT) and CNT-based systems possess unique chemical, physical, and biological properties that make them good candidates in biomedical applications, but they also have some inherent properties that cause great concern about their biosafety. This volume explores the practical applications of carbon nanotubes in biomedical science and human health. It discusses the synthesis, properties, modification, and recent progress of carbon nanotubes and their applications for biosensing, cancer treatment, antibacterial therapy, tissue engineering, targeted drug delivery, and toxicity. It relays the potential and promise of carbon-based nanomaterials for host of applications while also looking at the challenges in synthesis, characterization, and applications of nanomaterials and how to overcome them.
Cover
Half Title
Carbon Nanotubes for Biomedical Applications and Healthcare
Copyright
About the Editors
Contents
Contributors
Abbreviations
Preface
Part I. Fundamentals
1. Biomedical Applications of Carbon Nanotubes
Abstract
1.1 Introduction
1.2 Functionalization of CNT
1.2.1 Covalent Functionalization
1.3 Biomedical Applications of CNT
1.3.1 Biosensor
1.3.2 Drug Delivery
1.4 Toxicity of CNT
1.5 Conclusion
Acknowledgment
Keywords
References
2. Biotechnological and Biomedical Applications of CNTs
Abstract
2.1 Introduction
2.2 Carbon Nanotubes as Biosensors
2.2.1 CNT-Based Biosensors for Protein Biomarkers
2.2.2 CNT-Based Biosensors for Nucleic Acids Biomarkers
2.2.2.1 Microrna
2.3 Carbon Nanotubes in Biomedical Imaging
2.3.1 In Vitro Photoluminescence Imaging
2.3.2 In Vitro Raman Imaging
2.3.3 Swnts for in Vivo Animal Imaging
2.4 Carbon Nanotubes in Drug and Gene Delivery
2.5 Tissue Engineering and Regenerative Medicine
2.6 Conclusion
Keywords
References
3. Functionalized Carbon Nanotubes: Biomedical Applications
Abstract
3.1 Introduction
3.2 Functionalization of Carbon Nanotubes
3.2.1 Non-Covalent Functionalization
3.2.2 Covalent Functionalization
3.3 Toxicity of CNT
3.4 Structures
3.4.1 Weight of CNTS
3.4.2 Number of Walls
3.4.3 Length and Diameter of CNT
3.4.4 Effect of Functionalization on Toxicity
3.5 Exploring Carbon Nanotubes for Their Biomedical Applications
3.5.1 Carbon Nanotubes in Tissue Engineering
3.5.2 Carbon Nanotubes in Gene Therapy
3.5.3 Carbon Nanotubes in Protein Delivery
3.5.4 Carbon Nanotubes as Biosensors
3.5.5 CNT Used in Biomedical Imaging
3.5.6 CNTs used as Delivery Carrier for Cancer Therapy
Keywords
References
4. Application of Carbon Nanotubes for Targeted Drug Delivery
Abstract
4.1 Introduction
4.2 Carbon Nanotubes: an Overview
4.3 Carbon Nanotubes as Drug Delivery System
4.4 Summary
Keywords
References
Part II. Carbon Nanotubes for Medical Diagnosis and Therapy
5. Carbon Nanotubes in Cancer Diagnosis and Therapy
Abstract
5.1 Introduction
5.2 Carbon Nanotubes
5.3 CNT Functionalization
5.3.1 Non-Covalent Functionalization
5.3.2 Covalent Functionalization
5.4 Carbon Nanotubes in Cancer Diagnosis
5.4.1 Photoacoustic Imaging (PAI)
5.4.2 Raman Imaging
5.5 Carbon Nanotubes in Cancer Therapy
5.5.1 CNTs in Cancer Chemotherapy
5.5.2 CNTs in Targeted Drug Delivery
5.5.3 CNTs in Thermal Therapy
5.5.4 CNTs in Photothermal Therapy
5.5.5 CNTs in Gene Therapy
5.6 Toxicity of CNTs
5.7 Conclusion
Keywords
References
6. Carbon Nanotubes: As an Effective Opportunity for Diagnosis and Treatment of Cancer
7. Carbon Nanotubes: A Novel Approach in Management of Fatal Disease Cancer
8. Carbon Nanotubes: Application in Management of Alzheimerβs Disease
Part III. New Horizons in Sensing Technologies, Biomedical Imaging, and Health Care
9. Recent Advances in Carbon Nanotube-Based Electrochemical and Optical Biosensors
Abstract
9.1 Introduction
9.2 Biosensors
9.3 Optical Biosensors
9.4 Surface-Enhanced Raman Spectroscopy (SERS) Biosensor
9.5 Electrochemical Biosensors
9.6 Carbon Nanotube as Electrode-Electrochemical Biosensor
9.7 Carbon Nanotube in FET-Based Biosensor
9.8 Applications of Carbon-Based Materials for Virus Detection
9.8.1 Carbon Nanotubes in Human Virus Detection
9.8.2 Role of Carbon Nanotubes in Biosensors
9.8.3 Role of Electrochemical and Electronic CNT-Based Biosensors
9.8.4 CNTs-Based Electrochemical Biosensors for Cancer Detection and Treatment
9.8.5 Role of Optical CNT-Based Biosensors
9.8.6 Diagnosis of COVID-19
9.8.6.1 Naked Eye Diagnostic Test of COVID-19 Virus
9.8.7 Diagnosis of Dengue Virus
9.8.8 Diagnosis of Influenza Virus
9.8.9 Diagnosis of Human Immunodeficiency Virus (HIV)
9.8.10 Diagnosis of in Cancer Detection
9.8.10.1 Detection of Lung Cancer
9.8.10.2 Detection of Ovarian Cancer
9.8.10.3 Detection of Pancreatic Cancer
Keywords
References
10. Role of Carbon Nanotubes in Biosensor Developments
11. Carbon Nanotubes: A Promising Role in Biomedical Imaging
12. Carbon Nanotubes for Bioimaging
13. CNTs as Promising Adsorbents for Wastewater Purification
14. Carbon Nanotubes for Biomedical Applications and Health Care: New Horizons
Abstract
14.1 Introduction
14.2 Tissue Engineering
14.2.1 Advantages of CNTs in Scaffold Application
14.2.2 Bone Tissue Engineering and Regeneration Medicine
14.2.3 Cardiac Tissue Engineering and Regeneration Medicine
14.2.4 Nerves Tissue Engineering and Regeneration Medicine
14.2.5 Different Body Part Tissue Engineering and Regeneration Medicine
14.3 Biosensing
14.3.1 Bioreceptors
14.3.1.1 CNTs-Based Enzyme Biosensors
14.3.1.2 CNTs-Based Antibody Biosensors
14.3.1.3 CNTs-Based Nucleic Acid Biosensors
14.3.2 Transducers
14.3.2.1 Electrochemical Biosensors
14.3.2.2 CNTs-Based Amperometric Biosensors
14.3.2.3 CNTs-Based Potentiometric Biosensors
14.3.2.4 CNTs-Based Voltametric Biosensors
14.3.2.5 CNTs-Based Impedimetric Biosensors
14.3.3 Optical Biosensors
14.3.3.1 CNTs-Based Fluorescence Biosensors
14.3.3.2 CNTs-Based SPR Biosensors
14.3.4 Field-Effect Transistors Biosensors
14.4 Drug Delivery
14.4.1 Modification of CNTs
14.4.2 Drug Loading Mechanisms
14.4.3 Drug Delivery Mechanism
14.5 Bioimaging
14.5.1 Fluorescence Bioimaging
14.5.2 Raman Imaging
14.5.3 Magnetic Resonance Imaging
14.5.4 Photoacoustic Imaging
14.6 Toxicity
14.7 Conclusion
Keywords
References
Index
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