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Carbon-linked galactosphingolipid analogs bind specifically to HIV-1 gp120

✍ Scribed by Bertozzi, Carolyn R.; Cook, David G.; Kobertz, William R.; Gonzalez-Scarano, Francisco; Bednarski, Mark D.

Book ID
126057058
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
963 KB
Volume
114
Category
Article
ISSN
0002-7863

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We examined the binding of the gp120 envelope glycoprotein (gp120) of the human immunodeficiency virus (HIV-1) to sulfatide (Gals), galactocerebroside (GalC), and GM1-ganglioside (GM1). The gp120 glycoprotein bound to Gals but not to GalC or GM1 by enzyme-linked immunosorbent assay (ELISA) and by an