Carbon-13 NMR shift data of some 3H-1,4-benzodiazepine-2,5(1H, 4H)-diones
β Scribed by Ghulam Mohiuddin; Padala Satyanarayana Reddy; Chengalvala Venkata Ratnam
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 145 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0749-1581
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β¦ Synopsis
Carbon-13 chemical shifts of eight 3H-1,4-benzodiazepine-2,5( lH, 4H)-diones are reported. The carbonyl chemical shifts have diagnostic value for distinguishing these diones from the isomeric 1,3-benzodiazepine-2,5-dione structures.
π SIMILAR VOLUMES
The ring mobility of some 1,5-benzodiazepine-2,4-diones and 1,4-benzodiazepin-2-one has been investigated by lhe temperature dependence of their 'H NMR spectra. The activation parameters have been obtained, and the influence of N-1 substitution on the ring mobiity is discussed, takiig into account p
## Abstract Pentadeuteriophenyl clobazam 5 was synthesized in essentially quantitative isotopic purity, and characterized by ^1^HβNMR and mass spectroscopy. The title compound was found to be β₯98% pure by HPLC, and its retention time (t~R~ 6.17 min) was less than that of an authentic clobazam stand
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