✦ LIBER ✦

Carbocycles from carbohydrates: A simple route to an enantiomerically pure prostaglandin intermediate

✍ Scribed by Pascale Bélanger; Petpiboon Prasit

Publisher: Elsevier Science
Year: 1988
Tongue: French
Weight: 211 KB
Volume: 29
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)80802-3

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✦ Synopsis

The enone 7 , the key intermediate in the three component coupling approach to prostaglandins, has been prepared efficiently from commercially available D-ribonic acid y-lactone by an intramolecular aldol condensation .

Recent successes in the field of prostaglandin synthesis by Noyori' and Johnson2 using

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