A simple route to an enantiomerically pure diphosphine ligand containing a phosphorus stereogenic centre.

Carbocycles from carbohydrates: A simple

Carbocycles from carbohydrates: A simple route to an enantiomerically pure prostaglandin intermediate

✍ Pascale Bélanger; Petpiboon Prasit 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 211 KB

The enone 7 , the key intermediate in the three component coupling approach to prostaglandins, has been prepared efficiently from commercially available D-ribonic acid y-lactone by an intramolecular aldol condensation . Recent successes in the field of prostaglandin synthesis by Noyori' and Johnson