Mechanisms of elimination and substituti
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Qingshui Meng; Baoan Du; Alf Thibblin
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Article
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1999
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John Wiley and Sons
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English
⚖ 78 KB
The reactions of 4-(4'-nitrophenyl)-4-X-butan-2-one (1-X; X = Cl, OTs) with added bases/nucleophiles exhibit second-order kinetics. These substitution and elimination reactions are concluded to be of concerted S N 2 type and irreversible E1cB type, respectively. The spontaneous formation of alkene f